Nocita® (bupivacaine liposome injectable suspension)
Nocita® (bupivacaine liposome injectable suspension)
Pain and dysphoria don’t have to be part of the post-op experience.* Nocita is the only long-acting local anesthetic that controls post-op pain for up to 72 hours.
*In a field trial, Nocita reduced the need for post-op rescue pain treatment with opioids.
Raising the standard of modern recovery care
Nocita helps pets recover comfortably, even after going home
• Up to 72-hour analgesia
• Controls pain to help post-op return to function
• Single-dose administration
• Less opioid use1
• Reduced opioid-associated side effects, including dysphoria
• Discharge patients sooner, possibly equalizing or reducing cost of care
• Potentially improving client satisfaction
NOCITA is the only long-acting local anesthetic that controls post-op pain for up to 72 hours to help dogs undergoing cranial cruciate ligament (CCL) surgery recover comfortably, even after going home.
How does Nocita work?
Extended-release bupivacaine technology
Nocita is a sterile aqueous suspension of multivesicular liposomes containing bupivacaine. The liposomes are microscopic structures designed to gradually release bupivacaine from the vesicles:
• Liposomes do not diffuse readily from where they are deposited
• Bupivicane diffuses locally into surrounding tissues
This sustained-release formulation limits analgesic gaps
In a 2020 study, analgesia provided by Nocita® (bupivacaine liposome injectable suspension) resulted in a reduction in systemic opioid requirements:1
- Total number of rescue opioid doses was significantly lower in the Nocita group
- Total amount of rescue opioids administered was significantly lower in the Nocita group
The Nocita Difference
“Nocita has added to our clients’ confidence in their pets’ health care. They feel that we
are true heroes because we are sending their pet home looking like their pet instead of
looking drugged and not ready to come home.”
-Donna Sisak, CVT, VTS, Anesthesia
Seattle Veterinary Specialists - 2021
PROVEN CLINICAL EFFICACY AND DEMONSTRATED SAFETY IN DOGS2
- Proven pain control for up to 72 hours following canine CCL* surgery
- Well-tolerated in dogs following CCL surgery
PROVEN CLINICAL EFFICACY AND DEMONSTRATED SAFETY IN CATS3
- Provided up to 72 hours of regional postoperative pain control with just one dose for cats undergoing onychectomy
- Demonstrated safety as a peripheral nerve block in cats undergoing onychectomy
Addressing pain at different levels of the pain pathway
Nocita®(bupivacaine liposome injectable suspension) Resources
Indication
For single-dose infiltration into the surgical site to provide local postoperative analgesia for cranial cruciate ligament surgery in dogs. For use as a peripheral nerve block to provide regional postoperative analgesia following onychectomy in cats.
Important Safety Information
NOCITA is for use in dogs and cats only. Do not administer concurrently with bupivacaine HCl, lidocaine or other amide local anesthetics. The safe use of NOCITA in dogs and cats with cardiac disease or with hepatic or renal impairment has not been evaluated. The safe use in dogs or cats younger than 5 months of age, that are pregnant, lactating, or intended for breeding has not been evaluated. The most common adverse reactions in dogs were discharge from incision, incisional inflammation and vomiting. The most common adverse reactions in cats were elevated body temperature and infection or chewing/licking at the surgical site. Click here to view full product label.